Professor Nigel B. Perry
- Professor Nigel B. Perry
- Natural products chemistry - Research Leader
- Tel: (03) 479 8354
- Location: Science II, 4s6
Natural products chemistry is about the compounds that give colour and flavour to our foods, scent to flowers, and inspiration for many of our life-saving drugs. My research areas are:
- New natural products: discovering new compounds in foods and in native plants, by isolation directed by biological assays, with structure identification by combined NMR spectroscopy and molecular modelling. We also study biosynthesis in plants and ecological roles of natural products.
- Synthetic organic chemistry (with Bill Hawkins and Dave Larsen): studies on biomolecules to understand the relationship between structure and biological activity, and to produce more active and selective compounds.
- Analytical chemistry: using NMR, LC, GC, MS and Raman microscopy, to locate and quantify plant metabolites, food bioactives and flavour chemicals.
My group is part of Plant & Food Research, a Crown Research Institute, with collaborators in other University of Otago departments including Botany, Food Science and Microbiology, and links to other universities, industry and government researchers around New Zealand and abroad. We collaborate with Ngai Tahu and other iwi on developing new products from NZ native plants.
- Elaine Burgess
- Nigel Joyce (Plant & Food Research Lincoln, LC-MS)
- Catherine Sansom
- Dr John van Klink
- Alistair Richardson (PhD candidate): Transport of Secondary Metabolites in New Zealand Native Plants and Crops
- Dr Oliver Watkins: Bioluminescence from the New Zealand glow worm
- Dr Daniel Killeen: Raman spectroscopy of plant bioactives
- Dr Lesley Larsen
Selected Recent Papers
Richardson ATB, Lord JM, Perry NB 2017. Phenylanthraquinones and flavone-C-glucosides from the disjunct Bulbinella in New Zealand. Phytochemistry 134: 64-70. http://dx.doi.org/10.1016/j.phytochem.2016.11.014
Killeen DP, Watkins OC, Sansom CE, Andersen DH, Gordon KC, Perry NB 2017. Fast Sampling, Analyses and Chemometrics for Plant Breeding: Bitter Acids, Xanthohumol and Terpenes in Lupulin Glands of Hops (Humulus lupulus). Phytochem. Analysis 28: 50-57. http://onlinelibrary.wiley.com/doi/10.1002/pca.2642/full
Nhu D, Larsen L, Perry NB, Larsen DS, Hawkins BC 2016. Sweet poisons: synthetic strategies towards tutin glycosides. Aust. J. Chem. http://dx.doi.org/10.1071/CH16429
Menzies IJ, Youard LW, Lord JM, Carpenter KL, van Klink JW, Perry NB, Schaefer HM, Gould KS 2016. Leaf colour polymorphisms: a balance between plant defence and photosynthesis. J. Ecology 104: 104-113. http://onlinelibrary.wiley.com/doi/10.1111/1365-2745.12494/abstract
Killeen DP, Larsen L, Dayan FE, Gordon KC, Perry NB, van Klink JW 2016. Nortriketones: Antimicrobial trimethylated acylphloroglucinols from mānuka (Leptospermum scoparium). J. Nat. Prod. 79(3): 564–569. http://pubs.acs.org/doi/abs/10.1021/acs.jnatprod.5b00968
For full list of publications see: http://www.researcherid.com/rid/G-5574-2010