University of Otago, New Zealand

Chemistry

Te Tari Hua-Ruanuku

Dr Jaydee Cabral

contact photo
Dr Jaydee Cabral
synthesis, physicochemical characterization, and in vitro/in vivo biocompatibility of Medical hydrogels, 3D bioprinting, regenerative medicine, tissue engineering
Tel: (03) 479 4897 or 479 7920
Location: Science II, 3n9
jcabral@chemistry.otago.ac.nz


Dr. Cabral received her Ph.D. in Biomedical Sciences with a concentration in biochemistry from Eastern Virginia Medical School and Old Dominion University, USA.  She was a visiting lecturer at California State University prior to her appointment as a postdoctoral fellow in the chemistry department at the University of Otago.  She  was promoted to research fellow in 2011. Her research involves an interdisciplinary approach between both the Health Science and Basic Science divisions in the development, physicochemical characterization, and biocompatibility of a chitosan/dextran based surgical hydrogel for the prevention of adhesion formation in ear, nose, and throat surgeries.  Her repertoire of techniques includes polymer synthesis, chemical and physical characterization techniques, microbiological analysis, in vitro tissue culture, and  in vivo mouse models.  Dr. Cabral is part of an interdisciplinary network of researchers, physicians and industry partners who developed a surgical hydrogel, Chitogel®, that is being commercialised.

Dr. Cabral recently received funding from Lottery Health and a University of Otago Major Equipment grant for the purchase of the latest in 3D bioprinting technology, the GeSIM 3.1 Bioscaffolder. As a result of bringing this one of a kind instrument to New Zealand, Dr. Cabral was awarded an Explorer HRC grant for the development of 3D bioprinted regenerative, vascularized skin constructs for the treatment of chronic and non-healing wounds.

Dr. Cabral collaborates with researchers nationally and internationally as demonstrated by her publications.

Selected Publications

V. Nelson, F. Dinnunhan, P. Turner, J. Faed, and JD Cabral. A chitosan/dextran-based hydrogel as a delivery vehicle of human bone-marrow derived mesenchymal stem cells. Biomed Mater 2017, 12(3): 035012. https://doi.org/10.1088/1748-605X/aa70f2.

S. Ghosh, J.D. Cabral, L.R. Hanton, and S.C. Moratti. Strong Poly(ethylene oxide) Based Gel Adhesives via Oxime cross-linking. Acta Biomater 2016 29: 206-214.

M.A. Aziz, J.D. Cabral, H.J.L. Brooks, M.A. McConnell, C. Fitzpatrick, L.R. Hanton, S.C. Moratti. In vitro biocompatibility and cellular interactions of a chitosan/dextran-based hydrogel for postsurgical adhesion prevention. J Biomed Mater Res Part B 2015:103B:332–341. DOI: 10.1002/jbm.b.33206.

J. D. Cabral, M. Roxburgh, Z. Shi, L. Liu, M. McConnell, G. Williams, N. Evans, L. R. Hanton, J. Simpson, S. C. Moratti, B. H. Robinson, P. J. Wormald, S. Robinson. Synthesis, physiochemical characterization, and biocompatibility of a chitosan/dextran-based hydrogel for postsurgical adhension prevention. J Mat Sci: Mat in Med. 2014; 25: 2743-2756, DOI: 10.1007/s10856-014-5292-3.

M.A. Aziz, J.D. Cabral, H.J. Brooks, L.R. Hanton, and S.C. Moratti. Antimicrobial properties of a chitosan/dextran-based hydrogel for surgical use. Antimicrobial Agents and Chemotherapy 2012; 56(1): 280-287.

https://www.cmdt.org.nz/staff-member/dr-jaydee-cabral

 

Dr Cabral with Bioprinter

A 2 ink printed scaffold with piezo pipetting